Positive breast signs include: pathological nipple discharge, asymmetric thickening or nodularity, skin changes (Peau d’ orange, Dimple sign, Erythema, Nipple excoriation, Scaling, eczema, rupture) , secondary inverted nipple and so on.
Axillary lymph nodes, ALNs. The ultrasound grade of ALNs was divided into negative group (including Type 1, Type 2, Type 3, and Type 4) or positive group (including Type 5 and Type 6) on the basis of cortical morphologic features. The cortical morphologic features of each type of lymph node were defined as: Type 1, hyperechoic, no visible cortex; Type 2, thin (< 3 mm) hypoechoic cortex; Type 3, hypoechoic cortex thicker than 3 mm; Type 4, generalized lobulated hypoechoic cortex; Type 5, focal hypoechoic cortical lobulation; Type 6, totally hypoechoic node with no hilum. When there wer multiple types of lymph nodes in the same patient, the one with the highest grade was selected for inclusion.
If the Her-2 expressed (0) or (1+) on immunohistochemistry (IHC), please select "negative"; If the Her-2 expressed (3+) on IHC, please select "positive"; For Her-2 (2+) expression, Her-2 status was determined with gene amplification by fluorescence in situ hybridization (FISH).